Anti-BAG2 Polyclonal Antibody
品牌：solarbio | 货号：K106984P
| 英文名称 | Anti-BAG2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | 0 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:8000-12000. IHC 1:50-200. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 24kDa |
| Gene ID | 9532 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BAG2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BAG2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O95816 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner |