Anti-Thioredoxin Polyclonal Antibody
品牌：solarbio | 货号：K106714P
| 英文名称 | Anti-Thioredoxin Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TRDX;TRX;TRX1;TXN |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 12kDa |
| Gene ID | 7295 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human Thioredoxin |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human Thioredoxin |
| Subcellular Locations | Nucleus Cytoplasm Secreted |
| Swiss Prot | P10599 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |