Anti-BCL-2 Polyclonal Antibody
品牌：solarbio | 货号：K106396P
| 英文名称 | Anti-BCL-2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PPP1R50;Apoptosis regulator Bcl 2;AW986256;B cell CLL/lymphoma 2;C430015F12Rik |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 26kDa |
| Gene ID | 569 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BCL-2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BCL-2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P10415 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release |