Anti-SPDL1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SPDL1 Polyclonal Antibody

品牌:solarbio | 货号:K006833P

英文名称 Anti-SPDL1 Polyclonal Antibody
宿主 Rabbit
别名 CCDC99
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 70kDa/59kDa
Gene ID 54908
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SPDL1
性状 液体
Public Immunogen Range Recombinant protein of human SPDL1
Subcellular Locations Nucleus
Swiss Prot Q96EA4
克隆类型 Polyclonal Antibody
背景资料 Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.