Anti-SPDL1 Polyclonal Antibody
品牌:solarbio | 货号:K006833P
| 英文名称 | Anti-SPDL1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CCDC99 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 70kDa/59kDa |
| Gene ID | 54908 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SPDL1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SPDL1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q96EA4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect. |