Anti-EPHB2 Polyclonal Antibody
品牌：solarbio | 货号：K006061P
| 英文名称 | Anti-EPHB2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CAPB;DRT;EK5;EPHT3;ERK;Hek5;PCBC;Tyro5 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 117kDa |
| Gene ID | 2048 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EPHB2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EPHB2 |
| Subcellular Locations | Cell membrane Cell projection Single-pass type I membrane protein axon dendrite |
| Swiss Prot | P29323 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. |