Anti-AIF1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-AIF1 Polyclonal Antibody

品牌:solarbio | 货号:K006764P

英文名称 Anti-AIF1 Polyclonal Antibody
宿主 Rabbit
别名 IBA1;IRT1;AIF-1;IRT-1
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 17kDa
Gene ID 199
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Full length fusion protein
性状 液体
Public Immunogen Range Full length fusion protein
Subcellular Locations Cytoplasm
Swiss Prot P55008
克隆类型 Polyclonal Antibody
背景资料 This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.