Anti-AIF1 Polyclonal Antibody
品牌:solarbio | 货号:K006764P
英文名称 |
Anti-AIF1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
IBA1;IRT1;AIF-1;IRT-1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
17kDa |
Gene ID |
199 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Full length fusion protein |
性状 |
液体 |
Public Immunogen Range |
Full length fusion protein |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P55008 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |