Anti-Dnmt1 Polyclonal Antibody
品牌：solarbio | 货号：K004038P
| 英文名称 | Anti-Dnmt1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Rat |
| 蛋白分子量 | 183kDa |
| Gene ID | 1786 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human Dnmt1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human Dnmt1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P26358 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. |