Anti-TAU Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TAU Polyclonal Antibody

品牌:solarbio | 货号:K101294P

英文名称 Anti-TAU Polyclonal Antibody
宿主 Rabbit
别名 DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 79kDa
Gene ID 4137
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TAU
性状 液体
Public Immunogen Range A synthetic peptide of human TAU
Subcellular Locations Cell membrane Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein axon cytoskeleton cytosol
Swiss Prot P10636
克隆类型 Polyclonal Antibody
背景资料 Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.