Anti-TAU Polyclonal Antibody
品牌:solarbio | 货号:K101294P
英文名称 |
Anti-TAU Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DDPAC;FTDP-17;MAPTL;MSTD;MTBT1;MTBT2;PPND;PPP1R103;TAU |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
79kDa |
Gene ID |
4137 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TAU |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TAU |
Subcellular Locations |
Cell membrane Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein axon cytoskeleton cytosol |
Swiss Prot |
P10636 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |