Anti-PEX3 Polyclonal Antibody
品牌：solarbio | 货号：K005196P
| 英文名称 | Anti-PEX3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PBD10A;PBD10B;TRG18 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 8504 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PEX3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PEX3 |
| Subcellular Locations | Multi-pass membrane protein Peroxisome membrane |
| Swiss Prot | P56589 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). |