Anti-CD105 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD105 Polyclonal Antibody

品牌:solarbio | 货号:K106547P

英文名称 Anti-CD105 Polyclonal Antibody
宿主 Rabbit
别名 END;HHT1;ORW1;ENG;Endoglin
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 53kDa
Gene ID 2022
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD105
性状 液体
Public Immunogen Range A synthetic peptide of human CD105
Subcellular Locations Membrane Single-pass type I membrane protein
Swiss Prot P17813
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.