Anti-HER2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-HER2 Polyclonal Antibody

品牌:solarbio | 货号:K106524P

英文名称 Anti-HER2 Polyclonal Antibody
宿主 Rabbit
别名 CD340;HER-2;HER-2/neu;HER2;MLN19;NEU;NGL;TKR1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 138kDa
Gene ID 2064
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human HER2
性状 液体
Public Immunogen Range A synthetic peptide of human HER2
Subcellular Locations Cell membrane Cytoplasm Nucleus Nucleus Single-pass type I membrane protein perinuclear region
Swiss Prot P04626
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.