Anti-OAT-3 Polyclonal Antibody
品牌：solarbio | 货号：K106496P
| 英文名称 | Anti-OAT-3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SLC22A8;hOAT3;S22A8_HUMAN;Organic anion transporter 3 |
| 应用 | WB |
| 稀释比例 | WB 1:3000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 9376 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human OAT-3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human OAT-3 |
| Subcellular Locations | Cell membrane |
| Swiss Prot | Q8TCC7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Human organic anion transporter (OAT) 3 (SLC22A8) is localized to the basolateral membranes of renal tubular epithelial cells and plays a critical role in the excretion of anionic compounds. Recent advances in molecular biology have identified three organic anion transporter families: the organic anion transporter (OAT) family encoded by SLC22A, the organic anion transporting peptide (OATP) family encoded by SLC21A (SLCO), and the multidrug resistance-associated protein (MRP) family encoded by ABCC. These families play critical roles in the transepithelial transport of organic anions in the kidneys as well as in other tissues such as the liver and brain. Among these families, the OAT family plays the central role in renal organic anion transport. Knowledge of these three families at the molecular level, such as substrate selectivity, tissue distribution, and gene localization, is rapidly increasing. |