Anti-MDC1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-MDC1 Polyclonal Antibody

品牌:solarbio | 货号:K007607P

英文名称 Anti-MDC1 Polyclonal Antibody
宿主 Rabbit
别名 NFBD1
应用 IHC
稀释比例 IHC 1:100-300.
交叉反应 Human
蛋白分子量 227/198/117kDa
Gene ID 9656
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human MDC1
性状 液体
Public Immunogen Range A synthetic peptide of human MDC1
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q14676
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.