Anti-BAK1 Polyclonal Antibody
品牌：solarbio | 货号：K006653P
| 英文名称 | Anti-BAK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BAK;CDN1;BCL2L7;BAK-LIKE |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-5000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 23kDa |
| Gene ID | 578 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human BAK1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human BAK1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q16611 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |