Anti-EXOC2 Polyclonal Antibody
品牌：solarbio | 货号：K005720P
| 英文名称 | Anti-EXOC2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SEC5;SEC5L1;Sec5p |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 104kDa |
| Gene ID | 55770 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EXOC2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EXOC2 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | Q96KP1 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. |