Anti-PRNP Polyclonal Antibody
品牌：solarbio | 货号：K003437P
| 英文名称 | Anti-PRNP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ASCR;AltPrP;CD230;CJD;GSS;KURU;PRIP;PrP;PrP27-30;PrP33-35C;PrPc;p27-30 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 9kDa |
| Gene ID | 5621 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PRNP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PRNP |
| Subcellular Locations | Cell membrane Cytoplasm GPI-anchor Golgi apparatus Lipid-anchor Nucleus |
| Swiss Prot | P04156 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. |