Anti-NDUFS1 Polyclonal Antibody
品牌:solarbio | 货号:K003443P
英文名称 |
Anti-NDUFS1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CI-75Kd;CI-75k;PRO1304 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
79kDa |
Gene ID |
4719 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human NDUFS1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human NDUFS1 |
Subcellular Locations |
Mitochondrion inner membrane |
Swiss Prot |
P28331 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. |