Anti-C4BPB Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-C4BPB Polyclonal Antibody

品牌:solarbio | 货号:K004460P

英文名称 Anti-C4BPB Polyclonal Antibody
宿主 Rabbit
别名 C4BP
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 28kDa
Gene ID 725
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human C4BPB
性状 液体
Public Immunogen Range Recombinant protein of human C4BPB
Subcellular Locations Secreted
Swiss Prot P20851
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.