Anti-C4BPB Polyclonal Antibody
品牌：solarbio | 货号：K004460P
| 英文名称 | Anti-C4BPB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | C4BP |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 28kDa |
| Gene ID | 725 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human C4BPB |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human C4BPB |
| Subcellular Locations | Secreted |
| Swiss Prot | P20851 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |