Anti-ANAPC5 Polyclonal Antibody
品牌:solarbio | 货号:K008308P
英文名称 |
Anti-ANAPC5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
APC5 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
85kDa |
Gene ID |
51433 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ANAPC5 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ANAPC5 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q9UJX4 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.? |