Anti-AKR1C3 Polyclonal Antibody
品牌:solarbio | 货号:K106744P
英文名称 |
Anti-AKR1C3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DDX;HAKRB;HSD17B5;KIAA0119;PGFS |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
37kDa |
Gene ID |
8644 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human AKR1C3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human AKR1C3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P42330 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |