Anti-BAX Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-BAX Polyclonal Antibody

品牌:solarbio | 货号:K008076P

英文名称 Anti-BAX Polyclonal Antibody
宿主 Rabbit
别名 BCL2L4
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 21kDa
Gene ID 581
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human BAX
性状 液体
Public Immunogen Range Recombinant protein of human BAX
Subcellular Locations Cytoplasm
Swiss Prot Q07812
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.