Anti-CLDN11 Polyclonal Antibody
品牌：solarbio | 货号：K007693P
| 英文名称 | Anti-CLDN11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | OSP;OTM |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 5010 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CLDN11 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CLDN11 |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | O75508 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. |