Anti-ADPRHL2 Polyclonal Antibody
品牌:solarbio | 货号:K007653P
英文名称 |
Anti-ADPRHL2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ARH3 |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
39kDa |
Gene ID |
54936 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ADPRHL2 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ADPRHL2 |
Swiss Prot |
Q9NX46 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria. |