Anti-ADPRHL2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ADPRHL2 Polyclonal Antibody

品牌:solarbio | 货号:K007653P

英文名称 Anti-ADPRHL2 Polyclonal Antibody
宿主 Rabbit
别名 ARH3
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse
蛋白分子量 39kDa
Gene ID 54936
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ADPRHL2
性状 液体
Public Immunogen Range A synthetic peptide of human ADPRHL2
Swiss Prot Q9NX46
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria.