Anti-ADPRHL2 Polyclonal Antibody
品牌:solarbio | 货号:K007653P
| 英文名称 | Anti-ADPRHL2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARH3 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 39kDa |
| Gene ID | 54936 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ADPRHL2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ADPRHL2 |
| Swiss Prot | Q9NX46 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria. |