Anti-SFXN1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SFXN1 Polyclonal Antibody

品牌:solarbio | 货号:K007252P

英文名称 Anti-SFXN1 Polyclonal Antibody
宿主 Rabbit
别名 TCC;sideroflexin-1
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human Mouse Rat
蛋白分子量 36kDa
Gene ID 94081
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SFXN1
性状 液体
Public Immunogen Range Recombinant protein of human SFXN1
Subcellular Locations Mitochondrion
Swiss Prot Q9H9B4
克隆类型 Polyclonal Antibody
背景资料 The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain.