Anti-Phospho-PTK2-Y397 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-PTK2-Y397 Polyclonal Antibody

品牌:solarbio | 货号:K006213P

英文名称 Anti-Phospho-PTK2-Y397 Polyclonal Antibody
宿主 Rabbit
别名 FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK
应用 WB
稀释比例 WB 1:500-1000.
交叉反应 Human Mouse Rat
蛋白分子量 119kDa
Gene ID 5747
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding Y397 of human PTK2
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding Y397 of human PTK2
Subcellular Locations Cell junction Cell membrane Cytoplasm Cytoplasmic side Nucleus Peripheral membrane protein cell cortex centrosome cytoskeleton focal adhesion microtubule organizing center
Swiss Prot Q05397
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined.