Anti-Phospho-H2AFX-S139 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-Phospho-H2AFX-S139 Polyclonal Antibody

品牌:solarbio | 货号:K006207P

英文名称 Anti-Phospho-H2AFX-S139 Polyclonal Antibody
宿主 Rabbit
别名 H2A.X;H2A/X;H2AX
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-100. IF 1:50-100.
交叉反应 Human Mouse Rat
蛋白分子量 15kDa
Gene ID 3014
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x
性状 液体
Public Immunogen Range A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x
Subcellular Locations Chromosome Nucleus
Swiss Prot P16104
克隆类型 Polyclonal Antibody
背景资料 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.