Anti-Phospho-H2AFX-S139 Polyclonal Antibody
品牌:solarbio | 货号:K006207P
英文名称 |
Anti-Phospho-H2AFX-S139 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
H2A.X;H2A/X;H2AX |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
15kDa |
Gene ID |
3014 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x |
性状 |
液体 |
Public Immunogen Range |
A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2A.x |
Subcellular Locations |
Chromosome Nucleus |
Swiss Prot |
P16104 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. |