Anti-SAFB Polyclonal Antibody
品牌：solarbio | 货号：K005561P
| 英文名称 | Anti-SAFB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HAP;HET;SAB-B1;SAF-B;SAF-B1;SAFB1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 103kDa |
| Gene ID | 6294 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SAFB |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SAFB |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15424 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a ‘transcriptosome complex’ in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene. |