Anti-MSH3 Polyclonal Antibody
品牌：solarbio | 货号：K004132P
| 英文名称 | Anti-MSH3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DUP;FAP4;MRP1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 127kDa |
| Gene ID | 4437 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MSH3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MSH3 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P20585 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. |