Anti-WNT4 Polyclonal Antibody
品牌：solarbio | 货号：K005478P
| 英文名称 | Anti-WNT4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SERKAL;WNT-4 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 39kDa |
| Gene ID | 54361 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human WNT4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human WNT4 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | P56705 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. |