Anti-PDE6B Polyclonal Antibody
品牌：solarbio | 货号：K004881P
| 英文名称 | Anti-PDE6B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CSNB3;CSNBAD2;PDEB;RP40;rd1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 98kDa |
| Gene ID | 5158 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PDE6B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PDE6B |
| Subcellular Locations | Lipid-anchor Membrane |
| Swiss Prot | P35913 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |