Anti-ANAPC5 Polyclonal Antibody
品牌：solarbio | 货号：K005020P
| 英文名称 | Anti-ANAPC5 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APC5 |
| 应用 | WB IHC IP |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IP 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 85kDa |
| Gene ID | 51433 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANAPC5 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANAPC5 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | Q9UJX4 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. |