Anti-ACTA1 Polyclonal Antibody
品牌:solarbio | 货号:K008297P
英文名称 |
Anti-ACTA1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACTA;ASMA;CFTD;MPFD;NEM1;NEM2;NEM3;CFTD1;CFTDM |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
42kDa |
Gene ID |
58 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ACTA1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ACTA1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P68133 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. |