Anti-ALAS1 Polyclonal Antibody
品牌:solarbio | 货号:K004581P
英文名称 |
Anti-ALAS1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ALAS;ALAS-H;ALAS3;ALASH;MIG4 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
71kDa |
Gene ID |
211 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ALAS1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ALAS1 |
Subcellular Locations |
Mitochondrion matrix |
Swiss Prot |
P13196 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. |