Anti-SIRT1 Polyclonal Antibody
品牌:solarbio | 货号:K106486P
英文名称 |
Anti-SIRT1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
SIR2;SIR2alpha;SIR2L1;SIR2-like protein 1;Hsir2 |
应用 |
WB |
稀释比例 |
WB 1:3000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
130kDa |
Gene ID |
23411 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human SIRT1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human SIRT1 |
Subcellular Locations |
Cytoplasm Nucleus Mitochondrion |
Swiss Prot |
Q96EB6 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |