Anti-IFT74 Polyclonal Antibody
品牌：solarbio | 货号：K007696P
| 英文名称 | Anti-IFT74 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CMG1;CCDC2;CMG-1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 69kDa |
| Gene ID | 80173 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human IFT74 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human IFT74 |
| Swiss Prot | Q96LB3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells. |