Anti-ATP7A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ATP7A Polyclonal Antibody

品牌:solarbio | 货号:K007678P

英文名称 Anti-ATP7A Polyclonal Antibody
宿主 Rabbit
别名 MK;MNK;DSMAX;SMAX3
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 163kDa
Gene ID 538
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ATP7A
性状 液体
Public Immunogen Range A synthetic peptide of human ATP7A
Subcellular Locations Cytoplasm
Swiss Prot Q04656
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.?