Anti-UPF1 Polyclonal Antibody
品牌：solarbio | 货号：K007655P
| 英文名称 | Anti-UPF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HUPF1;NORF1;RENT1;smg-2;pNORF1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 124kDa |
| Gene ID | 5976 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human UPF1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human UPF1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q92900 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.? |