Anti-UPF1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-UPF1 Polyclonal Antibody

品牌:solarbio | 货号:K007655P

英文名称 Anti-UPF1 Polyclonal Antibody
宿主 Rabbit
别名 HUPF1;NORF1;RENT1;smg-2;pNORF1
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 124kDa
Gene ID 5976
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human UPF1
性状 液体
Public Immunogen Range A synthetic peptide of human UPF1
Subcellular Locations Cytoplasm
Swiss Prot Q92900
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.?