Anti-ZFP42 Polyclonal Antibody
品牌:solarbio | 货号:K007656P
英文名称 |
Anti-ZFP42 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
REX1;ZNF754 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human |
蛋白分子量 |
35kDa |
Gene ID |
132625 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ZFP42 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ZFP42 |
Swiss Prot |
Q96MM3 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1. |