Anti-ZFP42 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ZFP42 Polyclonal Antibody

品牌:solarbio | 货号:K007656P

英文名称 Anti-ZFP42 Polyclonal Antibody
宿主 Rabbit
别名 REX1;ZNF754
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human
蛋白分子量 35kDa
Gene ID 132625
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ZFP42
性状 液体
Public Immunogen Range A synthetic peptide of human ZFP42
Swiss Prot Q96MM3
克隆类型 Polyclonal Antibody
背景资料 Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.