Anti-CCR8 Polyclonal Antibody
品牌：solarbio | 货号：K007395P
| 英文名称 | Anti-CCR8 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CY6;TER1;CCR-8;CKRL1;CDw198;CMKBR8;GPRCY6;CMKBRL2;CC-CKR-8 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 41kDa |
| Gene ID | 1237 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CCR8 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CCR8 |
| Subcellular Locations | cytoplasm |
| Swiss Prot | P51685 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. |