Anti-ACMSD Polyclonal Antibody
品牌:solarbio | 货号:K006867P
英文名称 |
Anti-ACMSD Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;Picolinate carboxylase |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
38kDa |
Gene ID |
130013 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ACMSD |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ACMSD |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q8TDX5 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS. |