Anti-ACE Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ACE Polyclonal Antibody

品牌:solarbio | 货号:K003493P

英文名称 Anti-ACE Polyclonal Antibody
宿主 Rabbit
别名 ACE1;CD143;DCP;DCP1
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 150kDa
Gene ID 1636
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ACE
性状 液体
Public Immunogen Range Recombinant protein of human ACE
Subcellular Locations Cell membrane Cytoplasm Secreted Single-pass type I membrane protein
Swiss Prot P12821
克隆类型 Polyclonal Antibody
背景资料 This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.