Anti-ADRA2A Polyclonal Antibody
品牌：solarbio | 货号：K003495P
| 英文名称 | Anti-ADRA2A Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ADRA2;ADRA2R;ADRAR;ALPHA2AAR;ZNF32 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 49kDa |
| Gene ID | 150 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ADRA2A |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ADRA2A |
| Subcellular Locations | Cell membrane Multi-pass membrane protein |
| Swiss Prot | P08913 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. |