Anti-WHSC1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-WHSC1 Polyclonal Antibody

品牌:solarbio | 货号:K005567P

英文名称 Anti-WHSC1 Polyclonal Antibody
宿主 Rabbit
别名 NSD2;WHSC1;KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS;
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 152kDa
Gene ID 7468
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human WHSC1
性状 液体
Public Immunogen Range Recombinant protein of human WHSC1
Subcellular Locations Chromosome Cytoplasm Nucleus
Swiss Prot O96028
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.