Anti-WHSC1 Polyclonal Antibody
品牌:solarbio | 货号:K005567P
英文名称 |
Anti-WHSC1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
NSD2;WHSC1;KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS; |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
152kDa |
Gene ID |
7468 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human WHSC1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human WHSC1 |
Subcellular Locations |
Chromosome Cytoplasm Nucleus |
Swiss Prot |
O96028 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. |