Anti-NUDT15 Polyclonal Antibody
品牌：solarbio | 货号：K005789P
| 英文名称 | Anti-NUDT15 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MTH2;NUDT15D |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 19kDa |
| Gene ID | 55270 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NUDT15 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NUDT15 |
| Subcellular Locations | Cytosol |
| Swiss Prot | Q9NV35 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. |