Anti-DR1 Polyclonal Antibody
品牌：solarbio | 货号：K004853P
| 英文名称 | Anti-DR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NC2;NC2-BETA;NC2B |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 19kDa |
| Gene ID | 1810 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DR1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q01658 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. |