Anti-RAD51B Polyclonal Antibody
品牌：solarbio | 货号：K004896P
| 英文名称 | Anti-RAD51B Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | R51H2;RAD51L1;REC2 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Mouse Rat |
| 蛋白分子量 | 42kDa |
| Gene ID | 5890 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant Protein of human RAD51B |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant Protein of human RAD51B |
| Subcellular Locations | Nucleus |
| Swiss Prot | O15315 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. |