Anti-AGO1 Polyclonal Antibody
品牌：solarbio | 货号：K004319P
| 英文名称 | Anti-AGO1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EIF2C;EIF2C1;GERP95;Q99;hAgo1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-1000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 97kDa |
| Gene ID | 26523 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AGO1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AGO1 |
| Subcellular Locations | Cytoplasm P-body |
| Swiss Prot | Q9UL18 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. |