Anti-ACTL6B Polyclonal Antibody
品牌:solarbio | 货号:K005019P
英文名称 |
Anti-ACTL6B Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACTL6;BAF53B;arpNalpha |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
47kDa |
Gene ID |
51412 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ACTL6B |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ACTL6B |
Subcellular Locations |
Nucleus |
Swiss Prot |
O94805 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. |