Anti-BCL2L11 Polyclonal Antibody
品牌：solarbio | 货号：K007923P
| 英文名称 | Anti-BCL2L11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BAM;BIM;BOD |
| 应用 | IHC |
| 稀释比例 | IHC 1:20-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22/13/19/9/4kDa |
| Gene ID | 10018 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BCL2L11 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BCL2L11 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O43521 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. |