Anti-NANOS1 Polyclonal Antibody
品牌:solarbio | 货号:K007934P
| 英文名称 | Anti-NANOS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NOS1;SPGF12 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 30kDa |
| Gene ID | 340719 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NANOS1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NANOS1 |
| Swiss Prot | Q8WY41 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Nanos1, also known as NOS1, is a 292 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one nanos-type zinc finger. Expressed at high levels in spermatogonia and present at lower levels in fetal ovaries, Nanos1 forms a complex with Pumilio 2 and functions to regulate the translation of select mRNAs, specifically via association with the 3’-UTR of its mRNA targets. Additionally, Nanos1 is required for the establishment and maintenance of germline stem cells, as it prevents their premature entry into oogenesis. |